For community college (CC) students, a potentially vulnerable population for alcohol consumption, the avenues for campus-based interventions are often restricted. Although readily available online, the Brief Alcohol Screening and Intervention for College Students (BASICS) program faces the ongoing hurdle of correctly identifying at-risk community college students and successfully connecting them to appropriate interventions. A novel social media platform was utilized in this study to detect students at risk and enable the timely delivery of BASICS.
This randomized controlled trial explored the usefulness and acceptance of Social Media-BASICS. Participants were selected from a pool of five community centers. Introductory procedures incorporated a survey and the building of social media networks. For nine consecutive months, social media profiles underwent a content analysis evaluation. Intervention prompts contained alcohol references that implied a rise or problematic alcohol consumption. Participants who manifested such content were randomly placed into the BASICS intervention group or a parallel active control group. hepatitis C virus infection The feasibility and acceptability of the plan were determined by employing measures and analyses.
A total of 172 CC students completed the baseline survey; their average age was 229 years, with a standard deviation of 318 years. Of the group, 81% were women, and a considerable number, specifically 67%, identified their ethnicity as White. Social media postings referencing alcohol were observed in 120 (70%) of the participants, subsequently leading to their inclusion in intervention programs. Ninety-four participants, representing 93%, from the randomized group, completed the pre-intervention survey within 28 days of receiving the invitation. A majority of the participants expressed positive acceptance regarding the intervention.
The intervention strategically combined two validated techniques: recognizing signs of problem alcohol use on social media and applying the Web-BASICS intervention. Investigative results point to the practicality of implementing novel online interventions targeted at chronic condition populations.
This intervention's approach consisted of two validated components: the identification of problematic alcohol use evident on social media and the implementation of the Web-BASICS intervention. The study's findings suggest that web-based interventions provide a practical approach to interact with and assist CC populations.

In patients undergoing cardiac surgery, studying the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and their resultant complications (euglycemic diabetic ketoacidosis [eDKA] rate, mortality, infection, hospital and cardiovascular intensive care unit [CVICU] length of stay).
A look back at previous instances.
In the academic medical center, a university hospital setting.
In cardiac surgery, the adult patients.
A comparison between SGLT2i use and the non-usage of SGLT2i.
Patients admitted to the hospital for cardiac surgery within 24 hours, between February 2, 2019, and May 26, 2022, were evaluated by the authors regarding SGLT2i prevalence and the frequency of eDKA. Appropriate statistical analyses, including Wilcoxon rank sum and chi-square tests, were applied to the outcomes. The cardiac surgery cohort comprised 1654 patients; 53 (32%) of these received SGLT2i preoperatively; a subgroup of 8 (151% of 53) experienced eDKA. The authors' study demonstrated no discernible differences in hospital length of stay (median [IQR] 45 [35-63] days versus 44 [34-56] days, p=0.46), CVICU length of stay (median [IQR] 12 [10-22] days versus 11 [10-19] days, p=0.22), 30-day mortality (19% versus 7%, p=0.31), or sternal infection rates (0% versus 3%, p=0.69) between patients who did and did not use SGLT2i. For patients receiving SGLT2i medication, hospital lengths of stay were similar for those with and without eDKA (51 [40-58] days versus 44 [34-63] days, p=0.76); conversely, the intensive care unit (ICU) stay was significantly longer for those with eDKA (22 [15-29] days compared to 12 [9-20] days, p=0.0042). The rarity of both mortality (0% vs 22%, p=0.67) and wound infections (0% vs 0%, p > 0.99) is comparable.
A significant 15% of patients receiving SGLT2i prior to their cardiac surgery experienced eDKA after the operation, which corresponded to a longer length of stay in the CVICU. Further studies on SGLT2i management during the perioperative period are essential.
Postoperative eDKA affected 15% of patients pre-cardiac surgery who were on SGLT2i medication, exhibiting a connection to a more protracted CVICU length of stay. Research into the effective management of SGLT2 inhibitors in the period surrounding surgery is a significant area for future investigation.

Cytoreductive surgery (CRS), while vital in peritoneal carcinomatosis, is characterized by a high morbidity due to the patient's catabolic state. Perioperative nutritional optimization is paramount to improving the results of surgical interventions. This systematic review explored the connection between preoperative nutritional status and nutrition interventions, and their impact on clinical outcomes for CRS patients undergoing HIPEC.
The protocol for a systematic review was pre-registered with PROSPERO (registration number: 300326). Eight electronic databases were scrutinized on May 8th, 2022, and the findings were detailed according to the PRISMA guidelines. Our analysis incorporated studies reporting on nutritional status in CRS/HIPEC patients, employing methods like screening, assessments, implemented interventions, or measurable nutrition-related clinical outcomes.
Among the 276 screened studies, a total of 25 studies were deemed suitable for the review process. Subjective Global Assessment (SGA), computed tomography-derived sarcopenia assessments, preoperative albumin levels, and body mass index (BMI) are commonly used nutrition assessment tools in CRS-HIPEC patients. Retrospective examinations of SGA application correlated postoperative results. Patients exhibiting malnutrition had a heightened susceptibility to postoperative infectious complications, as evidenced by statistically significant differences in SGA-B (p=0.0042) and SGA-C (p=0.0025). In two separate studies, malnutrition was strongly correlated with a greater length of hospital stay (p=0.0006, p=0.002), and another study revealed a connection between malnutrition and decreased overall survival (p=0.0006). A review of eight studies on preoperative albumin levels disclosed conflicting relationships with subsequent surgical outcomes. Five investigations demonstrated no association between BMI and morbidity rates. According to one study, the routine placement of nasogastric tubes (NGT) is not warranted.
Preoperative nutritional assessment strategies, including the SGA and objective sarcopenia measures, offer insights into the nutritional condition of CRS-HIPEC patients. medical entity recognition To prevent complications, the optimization of nutrition is essential.
Tools for preoperative nutritional assessment, specifically including SGA and objective sarcopenia measurements, help predict nutritional status in CRS-HIPEC patients. The optimization of nutritional intake is paramount in preventing the onset of complications.

Post-pancreatoduodenectomy, marginal ulcers find reduction through the use of proton pump inhibitors (PPIs). Even so, the role they play in the development of perioperative complications has yet to be determined.
In a retrospective review, we assessed the effect of postoperative proton pump inhibitors (PPIs) on perioperative outcomes within 90 days for all patients undergoing pancreatoduodenectomy at our institution from April 2017 through December 2020.
Of the 284 patients included, 206 (72.5%) received perioperative PPIs, representing a significant proportion of the sample compared to the 78 (27.5%) who did not receive them. The two cohorts were alike with regard to their demographic makeup and operative variables. The postoperative analysis showed a statistically significant (p<0.005) increase in both overall complications (743% in the PPI group versus 538% in the control group) and delayed gastric emptying (286% versus 115%) in the PPI group. In contrast, there was no difference in the occurrence of infectious complications, postoperative pancreatic fistula, or anastomotic leaks. In a multivariate analysis, PPI use was independently associated with an increased likelihood of overall complications (odds ratio 246, confidence interval 133-454) and a delay in gastric emptying (odds ratio 273, confidence interval 126-591), with a p-value of 0.0011 demonstrating statistical significance. Four postoperative patients, all of whom were given proton pump inhibitors, subsequently developed marginal ulcers within ninety days.
A substantial increase in the rate of overall complications and delayed gastric emptying was noted among patients who used proton pump inhibitors after undergoing a pancreatoduodenectomy.
A statistically significant relationship exists between postoperative proton pump inhibitor administration and a greater number of overall complications along with slower gastric emptying after undergoing pancreatoduodenectomy.

Laparoscopic pancreaticoduodenectomy (LPD) proves to be a difficult surgical procedure to master. A multidimensional analysis delved into the learning curve (LC) phenomenon in LPD.
Data pertaining to patients undergoing LPD surgery, carried out by a single surgeon between 2017 and 2021, served as the subject of this analysis. An in-depth, multi-faceted analysis of the LC was achieved using Cumulative Sum (CUSUM) and Risk-Adjusted (RA)-CUSUM methods.
One hundred thirteen patients were chosen. Conversion rates, postoperative complications overall, severe complications, and mortality presented as 4%, 53%, 29%, and 4%, respectively. The RA-CUSUM analysis revealed a competency progression in three stages: procedures 1-51 demonstrating baseline proficiency, procedures 52-94 signifying competency, and procedures exceeding 94 representing mastery. GLPG0187 A substantial decrease in operative time was observed in phases two and three, compared to phase one. Phase two experienced a reduction from 58,817 minutes to 54,113 minutes (p=0.0001), and phase three showed a reduction from 53,472 minutes to 54,113 minutes (p=0.0004). Mastery demonstrated a substantially reduced rate of severe complications compared to the competency phase (42% vs 6%, p=0.0005).